Endocrine Abstracts

Objective: The response of the hypothalamo-pituitary-adrenal axis to stress is mediated mainly through corticotrophin-releasing hormone and vasopressin. Accordingly, vasopressin levels are increased in septic shock. However, measurement of vasopressin is difficult because of its instability and short half-life. Copeptin is a more stable peptide derived from the same precursor molecule. This study aims to evaluate copeptin levels and its prognostic value in a prospective observ...